Structure determination of germacrane-type sesquiterpene alcohols from an endophyte Streptomyces griseus subsp.

Three germacrane-type sesquiterpene alcohols were isolated from an endophyte of mangrove plant Kandelia candel. Their structures were characterized as 1(10)E,5E-germacradiene-11-ol (1), 1(10)E,5E-germacradiene-3,11-diol (2), 1(10)E,5E-germacradiene-2,11-diol (3)based on the extensive NMR studies. Among them, 2 and 3 are identified as new compounds. Copyright (c) 2005 John Wiley & Sons, Ltd.