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Jeffrey W. Roberts et al.
ANNUAL REVIEW OF MICROBIOLOGY (2008)
(p)ppGpp: Still Magical?
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ANNUAL REVIEW OF MICROBIOLOGY (2008)
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Transient reversal of RNA polymerase II active site closing controls fidelity of transcription elongation
Maria L. Kireeva et al.
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The RNA polymerase II trigger loop functions in substrate selection and is directly targeted by α-amanitin
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Jamming the ratchet of transcription
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Structural basis of transcription inhibition by α-amanitin and implications for RNA polymerase II translocation
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Termination factor Rho and its cofactors NusA and NusG silence foreign DNA in E-coli
Christopher J. Cardinale et al.
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RNA polymerase: the vehicle of transcription
Sergei Borukhov et al.
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An allosteric path to transcription termination
Vitaly Epshtein et al.
MOLECULAR CELL (2007)
Allosteric control of the RNA polymerase by the elongation factor RfaH
Vladimir Svetlov et al.
NUCLEIC ACIDS RESEARCH (2007)
A central role of the RNA polymerase trigger loop in active-site rearrangement during transcriptional pausing
Innokenti Toulokhonov et al.
MOLECULAR CELL (2007)
Multisubunit RNA polymerases melt only a single DNA base pair downstream of the active site
Ekaterina Kashkina et al.
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Structural basis for transcription elongation by bacterial RNA polymerase
Dmitry G. Vassylyev et al.
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Structural basis for substrate loading in bacterial RNA polymerase
Dmitry G. Vassylyev et al.
NATURE (2007)
Stimulation of RNA polymerase II transcript cleavage activity contributes to maintain transcriptional fidelity in yeast
Hiroshi Koyama et al.
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Backtracking determines the force sensitivity of RNAP II in a factor-dependent manner
Eric A. Galburt et al.
NATURE (2007)
Structural basis of transcription: Role of the trigger loop in substrate specificity and catalysis
Dong Wang et al.
CELL (2006)
Abortive initiation and productive initiation by RNA polymerase involve DNA scrunching
Andrey Revyakin et al.
SCIENCE (2006)
Template misalignment in multisubunit RNA polymerases and transcription fidelity
Ekaterina Kashkina et al.
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The role of the largest RNA polymerase subunit lid element in preventing the formation of extended RNA-DNA hybrid
Tatyana Naryshkina et al.
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The role of the lid element in transcription by E-coli RNA polymerase
Innokenti Toulokhonov et al.
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Transcript-assisted transcriptional proofreading
Nikolay Zenkin et al.
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Kinetic investigation of Escherichia coli RNA polymerase mutants that influence nucleotide discrimination and transcription fidelity
Shannon F. Holmes et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
pH-dependent conformational switch activates the inhibitor of transcription elongation
Oleg Laptenko et al.
EMBO JOURNAL (2006)
Thermodynamic and kinetic modeling of transcriptional pausing (vol 103, pg 4439, 2006)
VR Tadigotla et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Thermodynamic and kinetic modeling of transcriptional pausing
VR Tadigotla et al.
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Functional interplay between the jaw domain of bacterial RNA polymerase and allele-specific residues in the product RNA-binding pocket
J Ederth et al.
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RNA polymerase II subunit Rpb9 is important for transcriptional fidelity in vivo
NK Nesser et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Crystal structure of Thermus aquaticus Gfh1 a Gre-factor paralog that inhibits rather than stimulates transcript cleavage
V Lamour et al.
JOURNAL OF MOLECULAR BIOLOGY (2006)
Regulation through the RNA polymerase secondary channel - Structural and functional variability of the coiled-coil transcription factors
J Symersky et al.
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Structural basis for transcription inhibition by tagetitoxin
DG Vassylyev et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2005)
Direct observation of base-pair stepping by RNA polymerase
EA Abbondanzieri et al.
NATURE (2005)
Response of RNA polymerase to ppGpp:: requirement for the ω subunit and relief of this requirement by DksA (vol 19, pg 2378, 2005)
CE Vrentas et al.
GENES & DEVELOPMENT (2005)
Structural basis of transcription inhibition by antibiotic streptolydigin
D Temiakov et al.
MOLECULAR CELL (2005)
Inhibition of bacterial RNA polymerase by streptolydigin: Stabilization of a straight-bridge-helix active-center conformation
S Tuske et al.
CELL (2005)
Allosteric modulation of the RNA polymerase catalytic reaction is an essential component of transcription control by rifamycins
I Artsimovitch et al.
CELL (2005)
NTP-driven translocation and regulation of downstream template opening by multi-subunit RNA polymerases
ZF Burton et al.
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Dynamic error correction and regulation of downstream bubble opening by human RNA polymerase II
XQ Gong et al.
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ppGpp:: a global regulator in Escherichia coli
LU Magnusson et al.
TRENDS IN MICROBIOLOGY (2005)
Nature of the nucleosomal barrier to RNA polymerase II
ML Kireeva et al.
MOLECULAR CELL (2005)
Conversion of active promoter-RNA polymerase complexes into inactive promoter bound complexes in e coli by the transcription effector, ppGpp
A Maitra et al.
MOLECULAR CELL (2005)
Bacterial transcription elongation factors: new insights into molecular mechanism of action
S Borukhov et al.
MOLECULAR MICROBIOLOGY (2005)
Thinking quantitatively about transcriptional regulation
SJ Greive et al.
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Structural, functional, and genetic analysis of sorangicin inhibition of bacterial RNA polymerase
EA Campbell et al.
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A ratchet mechanism of transcription elongation and its control
G Bar-Nahum et al.
CELL (2005)
The involvement of the aspartate triad of the active center in all catalytic activities of multisubunit RNA polymerase
V Sosunov et al.
NUCLEIC ACIDS RESEARCH (2005)
Structural basis for transcription regulation by alarmone ppGpp
I Artsimovitch et al.
CELL (2004)
The RNA polymerase II transcription cycle: cycling through chromatin
JQ Svejstrup
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Structural basis of transcription: Separation of RNA from DNA by RNA polymerase II
KD Westover et al.
SCIENCE (2004)
Transcription factors IIF and US and nucleoside triphosphate substrates as dynamic probes of the human RNA polymerase II mechanism
CF Zhang et al.
JOURNAL OF MOLECULAR BIOLOGY (2004)
DksA: A critical component of the transcription initiation machinery that potentiates the regulation of rRNA promoters by ppGpp and the initiating NTP
BJ Paul et al.
CELL (2004)
Regulation through the secondary channel-structural framework for ppGpp-DksA synergism during transcription
A Perederina et al.
CELL (2004)
Complete RNA polymerase II elongation complex structure and its interactions with NTP and TFIIS
H Kettenberger et al.
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Diffusion of nucleoside triphosphates and role of the entry site to the RNA polymerase II active center
NN Batada et al.
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α-amanitin blocks translocation by human RNA polymerase II
XQ Gong et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Structural basis of transcription: Nucleotide selection by rotation in the RNA polymerase II active center
KD Westover et al.
CELL (2004)
Molecular mechanism of transcription inhibition by peptide antibiotic microcin J25
K Adelman et al.
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Antibacterial peptide microcin J25 inhibits transcription by binding within and obstructing the RNA polymerase secondary channel
J Mukhopadhyay et al.
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Elongation by RNA polymerase II: the short and long of it
RJ Sim et al.
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Donation of catalytic residues to RNA polymerase active center by transcription factor Gre
E Sosunova et al.
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Transcription through the roadblocks:: the role of RNA polymerase cooperation
V Epshtein et al.
EMBO JOURNAL (2003)
Architecture of the RNA polymerase II-TFIIS complex and implications for mRNA cleavage
H Kettenberger et al.
CELL (2003)
Structure and function of the transcription elongation factor GreB bound to bacterial RNA polymerase
N Opalka et al.
CELL (2003)
NTP-driven translocation by human RNA polymerase II
YA Nedialkov et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Essential steps in the ppGpp-dependent regulation of bacterial ribosomal RNA promoters can be explained by substrate competition
L Jöres et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Cooperation between RNA polymerase molecules in transcription elongation
V Epshtein et al.
SCIENCE (2003)
Unified two-metal mechanism of RNA synthesis and degradation by RNA polymerase
V Sosunov et al.
EMBO JOURNAL (2003)
In vitro studies of transcript initiation by Escherichia coli RNA polymerase.: 1.: RNA chain initiation, abortive initiation, and promoter escape at three bacteriophage promoters
LLM Hsu et al.
BIOCHEMISTRY (2003)
The flap domain is required for pause RNA hairpin inhibition of catalysis by RNA polymerase and can modulate intrinsic termination
I Toulokhonov et al.
MOLECULAR CELL (2003)
Transcript cleavage factors GreA and GreB act as transient catalytic components of RNA polymerase
O Laptenko et al.
EMBO JOURNAL (2003)
Swing-gate model of nucleotide entry into the RNA polymerase active center
V Epshtein et al.
MOLECULAR CELL (2002)
Crystal structure of a bacterial RNA polymerase holoenzyme at 2.6 Å resolution
DG Vassylyev et al.
NATURE (2002)
Structure-based analysis of RNA polymerase function: the largest subunit's rudder contributes critically to elongation complex stability and is not involved in the maintenance of RNA-DNA hybrid length
K Kuznedelov et al.
EMBO JOURNAL (2002)
Structural basis of transcription:: α-Amanitin-RNA polymerase II cocrystal at 2.8 A resolution
DA Bushnell et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Characterization of monoclonal antibodies against Escherichia coli core RNA polymerase
J Rouby et al.
BIOCHEMICAL JOURNAL (2002)
Transcript cleavage by Thermus thermophilus RNA polymerase.: Effects of GreA and anti-GreA factors.
BP Hogan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Control of intrinsic transcription termination by N and NusA: The basic mechanisms
I Gusarov et al.
CELL (2001)
TFIIS enhances transcriptional elongation through an artificial arrest site in vivo
D Kulish et al.
MOLECULAR AND CELLULAR BIOLOGY (2001)
Structural basis of transcription:: RNA polymerase II at 2.8 Ångstrom resolution
P Cramer et al.
SCIENCE (2001)
Structural basis of transcription:: An RNA polymerase II elongation complex at 3.3 Å resolution
AL Gnatt et al.
SCIENCE (2001)
Structural mechanism for rifampicin inhibition of bacterial RNA polymerase
EA Campbell et al.
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Bacterial RNA polymerase subunit ω and eukaryotic RNA polymerase subunit RPB6 ave sequence, structural, and functional homologs and promote RNA polymerase assembly
L Minakhin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Mechanism of regulation of transcription initiation by ppGpp. II. Models for positive control based on properties of RNAP mutants and competition for RNAP
MM Barker et al.
JOURNAL OF MOLECULAR BIOLOGY (2001)
Binding of the transcription effector ppGpp to Escherichia coli RNA polymerase is allosteric, modular, and occurs near the N terminus of the β′-subunit
II Toulokhonov et al.
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RNA polymerase: Structural similarities between bacterial RNA polymerase and eukaryotic RNA polymerase II
RH Ebright
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Function of transcription cleavage factors GreA and GreB at a regulatory pause site
MT Marr et al.
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A structural model of transcription elongation
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SCIENCE (2000)
Overextended RNA:DNA hybrid as a negative regulator of RNA polymerase II processivity
ML Kireeva et al.
JOURNAL OF MOLECULAR BIOLOGY (2000)
The 8-nucleotide-long RNA:DNA hybrid is a primary stability determinant of the RNA polymerase II elongation complex
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