期刊
ANNUAL REVIEW OF ANALYTICAL CHEMISTRY
卷 1, 期 -, 页码 423-449出版社
ANNUAL REVIEWS
DOI: 10.1146/annurev.anchem.1.031207.113042
关键词
microenvironment; extracellular matrix; microfabrication
资金
- University of Wisconsin, Madison MMB laboratory
Microfluidic technology holds great promise for the creation of advanced cell culture models. In this review, we discuss the characterization of cell cult-Lire in microfluidic systems, describe important biochemical and physical features of the cell microenvironment, and review studies of microfluidic cell manipulation in the context of these features. Finally, we consider the integration of analytical elements, ways to achieve high throughput, and the design constraints imposed by cell biology applications.
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