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RNA helicases: Versatile ATP-driven nanomotors

期刊

JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
卷 5, 期 12, 页码 1983-1989

出版社

AMER SCIENTIFIC PUBLISHERS
DOI: 10.1166/jnn.2005.508

关键词

molecular motor; nucleic acid; RNA; ATP; protein; P-loop; unwinding; DEAD-box; DExH; helicase

资金

  1. NIGMS NIH HHS [R01 GM067700-01, R01 GM067700] Funding Source: Medline

向作者/读者索取更多资源

RNA helicases are a large family of molecular motors that utilize nucleoside triphosphates to unwind RNA duplexes and to remodel RNA protein complexes. In this review, we discuss the structure and function of RNA helicases with an emphasis on the potential application of these enzymes to control conformational changes in nanoassemblies that contain RNA.

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