期刊
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
卷 26, 期 6, 页码 473-478出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.ijantimicag.2005.09.005
关键词
anti microbial resistance surveillance; Escherichia coli; normalised resistance interpretation; interpretive zone breakpoints; disk diffusion test
Fifty faecal samples front healthy adults were grown on MacConkey agar and three pink colonies were subcultured, identified to species level and their antimicrobial susceptibility determined. Forty-seven samples yielded 141 isolates of Escherichia coli that were susceptible to most antimicrobials. Resistance was noted For ampicillin (30.5%), chloramphenicol (12.1%), tetracycline (23.4%), trimethoprim (24.8%) and co-trimoxazole (22.7%). A direct faecal plating method was used for extended resistance screening with E. coli as the indicator organism. Zone breakpoints were determined using normalisect resistance interpretation and gave similar Susceptibility results. Eighty-eight isolates of E. coli from within the zones of inhibition revealed four times more antimicrobial resistance. Extended antimicrobial resistance screening both provides the Susceptibility profile of the dominant E. coli isolate and detects greater resistance in rare isolates. (c) 2005 Elsevier B.V. and the International Society of Chemotherapy. All rights reserved.
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