期刊
ANNALS OF NEUROLOGY
卷 58, 期 6, 页码 821-828出版社
WILEY
DOI: 10.1002/ana.20662
关键词
-
资金
- NINDS NIH HHS [1U01 NS 40069-01A2] Funding Source: Medline
Hypotheses that inflammation contributes to neonatal cerebral white matter damage have evolved over the last three decades. The latest, expanded here, suggests that the adaptive immune system contributes to the intensity and duration of the processes that result in damage to cerebral white matter in the fetus and newborn. We propose several mechanisms by which fetal T lymphocytes could be activated during fetal exposure to infection. These include specific recognition of bacterial antigens, specific recognition of autoantigens, polyclonal activation by Toll-like receptors, and bystander activation by cytokines.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据