As science has become much complex and sophisticated, greater attention is paid to scientific collaboration within recent bibliometric studies. A total of 6538 publications in Molecular Biology from China during 1999-2003, as indicated by data collected from database of the Science Citation Index Expanded - Web Edition, have been analyzed. A large proportion of publications have been authored by more than 3 scientists. The composition of publications grouped by collaboration patterns are: 1.58% non-collaborative papers, 42.43% local papers, 34.37% domestic papers and 21.62% international papers on average during the studied period. The countries with which China has collaborative links and their frequencies are all itemized to indicate the intensity of international collaboration in the field of Molecular Biology. Finally, the differences between the impact of wholly indigenous papers and internationally collaborative papers have been compared. The results indicate that foreign collaboration does contribute a lot to the improvement of the mainstream connectivity and international visibility.
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