期刊
AMERICAN JOURNAL OF THE MEDICAL SCIENCES
卷 330, 期 6, 页码 303-310出版社
ELSEVIER SCIENCE INC
DOI: 10.1097/00000441-200512000-00008
关键词
metabolic syndrome; hypertension; obesity; insulin resistance; dyslipidemia; microalbuminuria
The cause of hypertension in the metabolic syndrome is complex and multifactorial and all of the elements of the metabolic syndrome, including obesity, insulin resistance, and the characteristic dyslipidemia probably are involved in mediating changes ultimately resulting in hypertension and modifying its course. Of these elements, obesity may play the most important and pivotal role in creating the conditions that lead to hypertension in the metabolic syndrome. This is not to say that the other elements of the syndrome are less important, and, as we gain more insight into the processes involved, we should be able to better manage the disease and tailor our therapeutic interventions appropriately.
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