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Peptide dendrimers

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JOURNAL OF PEPTIDE SCIENCE
卷 11, 期 12, 页码 757-788

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WILEY
DOI: 10.1002/psc.721

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multiple antigen peptides (MAPs); peptide dendrimers; synthetic vaccine; multiple antigenic peptides

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Dendrimers are branched structures and represent a fast growing field covering many areas of chemistry. Various types of dendrimers differing in composition and structure are mentioned, together with their practical use spanning from catalysis, transport vehicles to synthetic vaccines. The main stress is given to peptide dendrimers, namely, multiple antigenic peptides (MAPs). Their synthesis, physicochemical proper-ties, biological activities, etc. have been described with many examples. MAPs can be used as diagnostics, mimetics, for complexation of different cations, as vaccines against parasites, bacteria, viruses, etc. Copyright (c) 2005 European Peptide Society and John Wiley & Sons, Ltd.

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