期刊
EXPERT REVIEW OF ANTICANCER THERAPY
卷 5, 期 6, 页码 1069-1078出版社
TAYLOR & FRANCIS LTD
DOI: 10.1586/14737140.5.6.1069
关键词
E-cadherin; extracellular matrix; fibroblasts; insulin growth factor-1 integins; melanocyte; melanoma; stroma; transforming growth factor-beta
类别
Classically, cancer is thought of as a genetic disease, where the step-wise acquisition of mutations initiates and drives progression. More recent thinking posits that, although cancers are initiated through genetic mutation, progression is often the result of dynamic interactions between the tumor cells and their surrounding environment.
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