4.5 Article

Significant reduction of sperm disomy in six men: effect of traditional Chinese medicine?

期刊

ASIAN JOURNAL OF ANDROLOGY
卷 7, 期 4, 页码 419-425

出版社

WOLTERS KLUWER MEDKNOW PUBLICATIONS
DOI: 10.1111/j.1745-7262.2005.00068.x

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traditional Chinese medicine; sperm disomy; chromosome; male infertility

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Aim: To test the hypothesis that levels of sperm disomy fell significantly in six men treated by traditional Chinese medicine (TCM). Methods: Fluorescence in situ hybridization (FISH) was done on the sperm heads of six men before and during treatment by TCM. Results: There was a significant reduction in sperm disomy in all six men. This coincided with TCM treatment. Conclusion: This is the first study reporting a significant reduction in sperm disomy in men over a given time course. The fact that this coincided with TCM treatment is intriguing but no conclusions can be drawn from this until placebo-controlled clinical trials are implemented.

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