期刊
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
卷 15, 期 23, 页码 5284-5287出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bmcl.2005.08.046
关键词
synthesis; bisheterocycle-containing compounds; anti-influenza virus
A series of novel 4,2-bisheterocycle tandem derivatives consisting of a methyloxazole and thiazole subunit were synthesized. Many compounds were found to inhibit human influenza A virus. Several analogues exhibited moderate biological activity and could serve as leads for further optimizations for antivirus research. (c) 2005 Elsevier Ltd. All rights reserved.
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