期刊
SCIENCE
卷 310, 期 5753, 页码 1456-1460出版社
AMER ASSOC ADVANCEMENT SCIENCE
DOI: 10.1126/science.1114021
关键词
-
资金
- NIGMS NIH HHS [R01 GM057720, R01 GM048746, GM43756, R01 GM048746-14, GM057720, GM48746, R01 GM043756] Funding Source: Medline
Transformation and conjugation permit the passage of DNA through the bacterial membranes and represent dominant modes for the transfer of genetic information between bacterial cells or between bacterial and eukaryotic cells. As such, they are responsible for the spread of fitness-enhancing traits, including antibiotic resistance. Both processes usually involve the recognition of double-stranded DNA, followed by the transfer of single strands. Elaborate molecular machines are responsible for negotiating the passage of macromolecular DNA through the layers of the cell surface. All or nearly all the machine components involved in transformation and conjugation have been identified, and here we present models for their roles in DNA transport.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据