期刊
SCIENCE
卷 310, 期 5754, 页码 1680-1683出版社
AMER ASSOC ADVANCEMENT SCIENCE
DOI: 10.1126/science.1115327
关键词
-
资金
- NIMH NIH HHS [R01 MH067681] Funding Source: Medline
- NINDS NIH HHS [P01 NS19632] Funding Source: Medline
Much is known about how people make decisions under varying levels of probability (risk). Less is known about the neural basis of decision-making when probabilities are uncertain because of missing information (ambiguity). In decision theory, ambiguity about probabilities should not affect choices. Using functional brain imaging, we show that the level of ambiguity in choices correlates positively with activation in the amygdala and orbitofrontal cortex, and negatively with a striatal system. Moreover, striatal activity correlates positively with expected reward. Neurological subjects with orbitofrontal lesions were insensitive to the level of ambiguity and risk in behavioral choices. These data suggest a general neural circuit responding to degrees of uncertainty, contrary to decision theory.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据