A convenient procedure for palladium catalyzed cyanation using a unique bidentate phosphorus ligand

A palladium complex bearing 1,2-diphenyl-3,4-diphosphinidenecyclobutene ligand (DPCB) has been used to facilitate the catalytic cyanation of aryl bromides. A series of substituted benzonitriles was prepared in good to high yields by the treatment of the corresponding aryl bromides with Zn(CN)(2) in N-methyl-2-pyrrolidone in the presence of 2-4 mol % catalyst at 100 degrees C for 16 h. (c) 2005 Elsevier Ltd. All rights reserved.