期刊
COORDINATION CHEMISTRY REVIEWS
卷 249, 期 24, 页码 2845-2853出版社
ELSEVIER SCIENCE SA
DOI: 10.1016/j.ccr.2005.03.005
关键词
cancer; chemotherapy; cisplatin; platinum; toxicity; targeting
Selective drug delivery is an important approach with great potential for overcoming problems associated with the systemic toxicity of chemotherapy, in particular, platinum-based chemotherapy. Finding successful strategies for the targeting of platinum anticancer drugs has therefore been a subject of extensive research. This review paper gives an overview of some of the different approaches that have recently been used in the development of targeted platinum anticancer drugs. (c) 2005 Elsevier B.V. All rights reserved.
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