期刊
VIROLOGY
卷 344, 期 1, 页码 111-118出版社
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.virol.2005.09.028
关键词
persistent infection; T cell function; dendritic cell function; immune clearance; differentiated function
类别
资金
- NIAID NIH HHS [AI009484, AI036222, AI045927, AI055540] Funding Source: Medline
For a virus to persist, it must actively curtail the host's antiviral immune response. Here, we review the conceptual basis by which this can occur and discuss the subsequent fate of differentiated cells infected over long periods of time. We also consider how the compromised antiviral immune response can be revigorated or replaced with a potent response that purges the virus and thereby terminates persistent infection. (c) 2005 Elsevier Inc. All rights reserved.
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