期刊
SCIENCE
卷 311, 期 5758, 页码 242-245出版社
AMER ASSOC ADVANCEMENT SCIENCE
DOI: 10.1126/science.1123231
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资金
- NIGMS NIH HHS [P01 GM66521] Funding Source: Medline
Magnetosomes are membranous bacterial organelles sharing many features of eukaryotic organelles. Using electron cryotomography, we found that magnetosomes are invaginations of the cell membrane flanked by a network of cytoskeletal filaments. The filaments appeared to be composed of MamK, a homolog of the bacterial actin-like protein MreB, which formed filaments in vivo. In a mamK deletion strain, the magnetosome-associated cytoskeleton was absent and individual magnetosomes were no longer organized into chains. Thus, it seems that prokaryotes can use cytoskeletal filaments to position organelles within the cell.
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