期刊
CELL CYCLE
卷 5, 期 2, 页码 172-175出版社
TAYLOR & FRANCIS INC
DOI: 10.4161/cc.5.2.2343
关键词
cell cycle; stem cells; germ line; microRNA; Dicer; p21/p27/dacapo; checkpoint
类别
One of the key characteristics of stem cells is their capacity for self renewal for long periods of time. In this respect, stem cells are similar to cancer cells, which also have the ability to divide continuously. Therefore, a critical question in stem cell biology is how cell division is regulated in these cell types; too little division can result in defective tissue homeostasis, while too much can result in cancer. In this review, we summarize recent progress and describe future challenges to understanding the role the microRNA pathway plays in regulating mechanisms controlling stem cell division.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据