期刊
FEBS LETTERS
卷 580, 期 2, 页码 561-567出版社
WILEY
DOI: 10.1016/j.febslet.2005.12.062
关键词
quorum sensing; methylotroph; C-1 metabolism
Acyl-homoserine lactones (acyl-HSLs) have emerged as important regulatory molecules for many gram-negative bacteria. We have found that Methylobacterium extorquens AMI, a member of the pink-pigmented facultative methylotrophs commonly present on plant surfaces, produces several acyl-HSLs depending upon the carbon source. A novel HSL was discovered with a double unsaturated carbon chain (N-(tetradecenoyl)) (04:2) and characterized by MS and proton NMR. This long-chain acyl-HSL is synthesized by MlaI that also directs synthesis of C14:1-HSL. The Alphaproteobacterium also produces N-hexanoyl-HSL (C6-HSL) and N-octanoyl-HSL (C8-HSL) via Msal. (c) 2005 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.
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