期刊
OTOLARYNGOLOGY-HEAD AND NECK SURGERY
卷 134, 期 2, 页码 181-186出版社
SAGE PUBLICATIONS INC
DOI: 10.1016/j.otohns.2005.11.010
关键词
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OBJECTIVES: To determine whether meta-analysis Supports the use of corticosteroids to reduce post-tonsillectomy pain for pediatric patients. METHODS: A systematic review Of Currently available randomized controlled trials using a single-dose, intravenous corticosteroid during pediatric tonsillectomy was performed. Visual analog pain scale (VAS) data was extracted with reviewers blinded to results. Meta-analysis was performed with weighted mean difference and random-effects model using Revman 4.2 software. RESULTS: Eight randomized trials were included in analysis of post-tonsillectomy pain. A statistically significant reduction in pain as Measured by VAS oil postoperative day I was noted (mean VAS difference = -0.97 Cl 95 % = -1.74,-0.19 P = 0.01). CONCLUSIONS: A single, intraoperative close of dexamethasone may reduce post-tonsillectomy pain oil postoperative day 1, by a factor of 1 on a 10-point pain scale. As the side effects and cost of dexamethasone close appear negligible, consideration of routine use seems reasonable.
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