期刊
JOURNAL OF BIOLOGICAL RHYTHMS
卷 21, 期 1, 页码 13-20出版社
SAGE PUBLICATIONS INC
DOI: 10.1177/0748730405282882
关键词
Drosophila; egg laying; activity; eclosion; LNv; LNd; DN
The authors report the results of their study aimed at investigating the consequence of targeted ablation of ventral lateral neurons (LN(v)s-neurons regulating eclosion and locomotor activity rhythms) and genetic disruption of pigment-dispersing factor (PDF-an important output of circadian clocks) on the egg-laying rhythm of Drosoplida melanogaster. The results clearly suggest that genetic ablation of LN(v)s and loss of function mutation of PDF abolish eclosion and locomotor activity rhythms, whereas the egg-laying rhythm continues unabated. Furthermore, the results also demonstrate that the period of egg-laying rhythm remains unchanged under different ambient temperatures and nutrition levels, suggesting that the egg-laying rhythm of D. melanogaster is temperature and nutrition compensated. Based on these results, the authors conclude that the egg-laying rhythm in D. melanogaster is regulated by non-LNv-based, non-PDF-mediated circadian clocks.
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