期刊
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
卷 50, 期 2, 页码 765-769出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.50.2.765-769.2006
关键词
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Retapamulin had the lowest rate of spontaneous mutations by single-step passaging and the lowest parent and selected mutant MICs by multistep passaging among all drugs tested for all Staphylococcus aureus strains and three Streptococcus pyogenes strains which yielded resistant clones. Retapamulin has a low potential for resistance selection in S. pyogenes, with a slow and gradual propensity for resistance development in S. aureus.
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