4.8 Article

Artificial viruses: a nanotechnological approach to gene delivery

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NATURE REVIEWS DRUG DISCOVERY
卷 5, 期 2, 页码 115-121

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NATURE PUBLISHING GROUP
DOI: 10.1038/nrd1960

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Nanotechnology is a rapidly expanding multidisciplinary field in which highly sophisticated nanoscale devices are constructed from atoms, molecules or ( macro) molecular assemblies. In the field of gene medicine, systems for delivering nucleic acids are being developed that incorporate virus-like functions in a single nanoparticle. Although their development is still in its infancy, it is expected that such artificial viruses will have a great impact on the advancements of gene therapeutics.

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