期刊
BIOCHEMICAL SOCIETY TRANSACTIONS
卷 34, 期 -, 页码 73-76出版社
PORTLAND PRESS LTD
DOI: 10.1042/BST0340073
关键词
actin remodelling; A-kinase anchoring protein (AKAP); cytoskeletal organization; kinase anchoring; Wiskott-Aldrich syndrome protein verprolin homologous protein(WAVE protein)
The small GTPases Rho, Rac and Cdc42 (cell-division cycle 42) function as molecular switches to modulate the actin cytoskeleton. They achieve this by modulating the activity of downstream cellular targets. One group of Rho GTPase effectors, WAVE (Wiskott-Aldrich syndrome protein verprolin homologous)-1, WAVE-2 and WAVE-3, function as scaffolds for actin-based signalling complexes. The present review highlights current knowledge regarding the biochemistry of the WAVE signalling complexes and their biological significance.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据