期刊
EXPERT REVIEW OF PROTEOMICS
卷 3, 期 1, 页码 87-95出版社
FUTURE DRUGS LTD
DOI: 10.1586/14789450.3.1.87
关键词
cell cycle; drug challenge; mass spectrometry; metabolic labeling; post-translational modifications; quantitative proteomics; subproteome analysis
资金
- Wellcome Trust [073896] Funding Source: Medline
The lethal species of malaria parasite, Plasmodium falciparum, continues to exact a huge toll of mortality and morbidity, particularly in sub-Saharan Africa. Completion of the genome sequence of this organism and advances in proteomics and mass spectrometry have opened up unprecedented opportunities for understanding the complex biology of this parasite and how it responds to drug challenge and other interventions. This review describes recent progress that has been made in applying proteomics technology to this important pathogen and provides a look forward to likely future developments.
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