期刊
JOURNAL OF CLINICAL EPIDEMIOLOGY
卷 59, 期 2, 页码 201-207出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.jclinepi.2005.06.007
关键词
cataract; cataract extraction; quality of life; treatment outcome; visual acuity; binocular vision
Background and Objective: Despite recommendation of surgery in both eyes in patients with bilateral cataract, there is little evidence about the benefits of second-eye surgery. The objective of this study was to compare the benefits of cataract surgery in both eyes with those of surgery in one eye only. Study Design and Setting: Two-arm randomized controlled trial involving 296 patients with bilateral cataracts of two public teaching hospitals. Patients were randomly assigned to receive surgery in one eye only (control group) or surgery in both eyes, one eye at a time (intervention group). The main outcome measures were binocular visual acuity, binocular contrast sensitivity, stereopsis, and patient-reported visual disability (VF-14), measured 4-6 months postoperatively. Results: A total of 135 (91.2%) and 139 (93.9%) patients completed the trial in the control and intervention groups, respectively. Postoperatively, intervention group presented a better visual acuity (difference of 0.07; 95% CI = 0.03, 0.12), stereopsis (0.62 log sec are; 95% CI = 0.45, 0.79), and VF-14 (8.2 points; 95% Cl = 4.4, 12.4). No significant differences were found for contrast sensitivity. Conclusions: Bilateral cataract patients should have surgery in both eyes. Including stereopsis and patient-reported visual disability in the assessment of cataract patients, especially after first-eye surgery, will improve the evaluation of effectiveness. (c) 2006 Elsevier Inc. All rights reserved.
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