期刊
BRAIN RESEARCH
卷 1071, 期 1, 页码 91-96出版社
ELSEVIER
DOI: 10.1016/j.brainres.2005.11.071
关键词
stress; post-inflammatory; corticotropin-releasing factor; paraventricular nucleus of the hypothalamus
资金
- NIDDK NIH HHS [DK57028] Funding Source: Medline
This study examined the long-term effects of an acute colitis on central corticotropin-releasing factor (CRF) expression. An increase in CRF mRNA in the paraventricular nucleus of the hypothalamus (PVN) and the central nucleus of the amygdala (CeA) was observed during active colitis, and the effect in the PVN was maintained following recovery. In summary, hypothalamic gene expression of CRF persists in the PVN despite resolution of an acute colitis. (C) 2005 Elsevier B.V. All rights reserved.
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