4.7 Article

The benefits of the multi-target approach in drug design and discovery

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BIOORGANIC & MEDICINAL CHEMISTRY
卷 14, 期 4, 页码 896-897

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PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bmc.2005.09.011

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drug design; promiscuous drug; cancer; Alzheimer's disease

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Promiscuous binding has been considered to be a problem in the design and development of new drugs against a given disease. However, promiscuity in Molecular recognition is not all bad news, and scientists are currently taking advantage of the emerging 'promiscuous binding' or 'multi-target approach' in medicinal chemistry. (c) 2005 Elsevier Ltd. All rights reserved.

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