期刊
NEUROREPORT
卷 17, 期 3, 页码 341-344出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/01.wnr.0000201509.53750.bc
关键词
consolidation; medial prefrontal cortex; memory retrieval; trace fear conditioning
资金
- NINDS NIH HHS [NS 35457, NS 049160] Funding Source: Medline
Declarative memories are thought to be initially stored in the hippocampus, and then transferred to the neocortex. This is a key feature of the standard model of consolidation and is supported by studies reporting a requirement for activity within the neocortex for recall of remote, but not recent, hippocampal-dependent memories. New evidence from our and other laboratories, however, suggests that, for trace fear conditioning, memories are stored in the rodent medial prefrontal cortex and in the hippocampus from the time of training. Consistent with this, we show that activity in the medial prefrontal cortex is necessary for retrieval of recent and remote memories, suggesting that information stored in this neocortical structure from the time of training is necessary for memory recall.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据