4.4 Article

Commensal bacteria influence Escherichia coli O157:H7 persistence and Shiga toxin production in the mouse intestine

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INFECTION AND IMMUNITY
卷 74, 期 3, 页码 1977-1983

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AMER SOC MICROBIOLOGY
DOI: 10.1128/IAI.74.3.1977-1983.2006

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  1. NIAID NIH HHS [T32 AI055406, R21-AI-02-008, T32-AI055406] Funding Source: Medline

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The presence of commensal flora reduced colonization of Escherichia coli O157:H7 and production of Shiga toxin (Stx) in the murine intestine. Stx production was not detected in mice colonized with E. coli that were resistant to the Shiga toxin phage, but it was detected in mice colonized with phage-susceptible E. coli.

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