期刊
DNA AND CELL BIOLOGY
卷 25, 期 3, 页码 189-196出版社
MARY ANN LIEBERT, INC
DOI: 10.1089/dna.2006.25.189
关键词
-
During evolution ribose was selected as the exclusive sugar component of nucleic acids. The selection is explained by using molecular models and by eliminating most of the other common sugars by looking at their chemical structure and envisioning how they would fit in a nucleic acid model. Comparisons of sugar pucker conformations and configurations of pentoses indicate that ribose was not randomly selected but the only choice, since beta-D-ribose fits best into the structure of physiological forms of nucleic acids. In other nucleotides containing arabinose, xylose, or lyxose, the C-2'-OH and/or the C-3'-OH are above the furanose ring, causing steric interference with the bulky base and the C-5'-OH group.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据