期刊
PEDIATRIC INFECTIOUS DISEASE JOURNAL
卷 25, 期 3, 页码 276-278出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/01.inf.0000202126.44544.41
关键词
tobramycin; aminoglycoside; ototoxicity; renal failure; cystic fibrosis
Tobramycin for inhalation is a mainstay of therapy for cystic fibrosis. Routine monitoring of serum concentrations is not performed for patients receiving tobramycin by this route. This is a case of an adolescent with cystic fibrosis, renal failure and a serum concentration of 13.4 mg/dL who was diagnosed with profound sensorineural hearing loss after 3 weeks of inhaled tobramycin therapy.
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