期刊
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
卷 142, 期 3-4, 页码 328-346出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.cbpc.2005.11.005
关键词
snake; venom; metalloprotease; disintegrin; structure; function
Snake venoms are relevant sources of toxins that have evolved towards the engineering of highly active compounds. In the last years, research efforts have produced great advance in their understanding and uses. Metalloproteases with disintegrin domains are among the most abundant toxins in many Viperidae snake venoms. This review will focus on the structure, function and possible applications of the metalloprotease and disintegrin domains. (c) 2005 Elsevier Inc. All rights reserved.
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