Acetylated flavonol diglucosides from Meconopsis quintuplinervia

Four acetylated flavonol diglucosides, quercetin 3-O-[2'-O-acetyl-O-D-glucopyranosyl-(1 -> 6)-beta-D-glucopyranoside] (1), quercetin 3-O-[2',6'-O-diacetyl-beta-D-glucopyranosyl-(1 -> 6)-beta-D-glucopyranoside] (2), isorhamnetin 3-O-[2'-O-acetyl-beta-D-glucopyranosyl-(1 -> 6)-beta-D-glucopyranoside] (3), and quercetin 3-O-[2'-O-acetyl-alpha-L-arabinopyranosyl-(1 -> 6)-beta-D-glucopyranoside] (4), together with five known flavonol glycosides quercetin 3-O-beta-D-glucopyranoside, kaempferol 3-O-beta-D-glucopyranoside, quercetin 3-O-[beta-D-galactopyranosyl-(1 -> 6)-glucopyranoside], isorhamnetin 3-O-[beta-D-galactopyranosyl-(1 -> 6)-beta-D-glucopyranoside], and kaempferol 3-O-[beta-D-glucopyranosyl-(1 -> 2)-beta-D-glucopyranoside] have been isolated from Meconopsis quintuplinervia. Their structures were determined using chemical and spectroscopic methods including HRFABMS, H-1-H-1 COSY, HSQC and HMBC experiments. (c) 2005 Elsevier Ltd. All rights reserved.