相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Autophagy and the Immune System
Petric Kuballa et al.
ANNUAL REVIEW OF IMMUNOLOGY, VOL 30 (2012)
Mechanisms and clinical significance of BIM phosphorylation in chronic lymphocytic leukemia
Alex Paterson et al.
BLOOD (2012)
Metabolic Signatures Uncover Distinct Targets in Molecular Subsets of Diffuse Large B Cell Lymphoma
Pilar Caro et al.
CANCER CELL (2012)
Sphingolipid Metabolism Cooperates with BAK and BAX to Promote the Mitochondrial Pathway of Apoptosis
Jerry E. Chipuk et al.
CELL (2012)
Genetically defining the mechanism of Puma- and Bim-induced apoptosis
S. P. Garrison et al.
CELL DEATH AND DIFFERENTIATION (2012)
Elevated Mcl-1 inhibits thymocyte apoptosis and alters thymic selection
K. J. Campbell et al.
CELL DEATH AND DIFFERENTIATION (2012)
BCL-2 family member BOK is widely expressed but its loss has only minimal impact in mice
F. Ke et al.
CELL DEATH AND DIFFERENTIATION (2012)
Anti-apoptotic Mcl-1 is essential for the development and sustained growth of acute myeloid leukemia
Stefan P. Glaser et al.
GENES & DEVELOPMENT (2012)
The BH3-Only Proteins Bim and Puma Cooperate to Impose Deletional Tolerance of Organ-Specific Antigens
Daniel H. D. Gray et al.
IMMUNITY (2012)
Oxidized Mitochondrial DNA Activates the NLRP3 Inflammasome during Apoptosis
Kenichi Shimada et al.
IMMUNITY (2012)
The Zinc-finger protein ASCIZ regulates B cell development via DYNLL1 and Bim
Sabine Jurado et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2012)
Anti-apoptotic MCL-1 localizes to the mitochondrial matrix and couples mitochondrial fusion to respiration
Rhonda M. Perciavalle et al.
NATURE CELL BIOLOGY (2012)
Reorganizing the protein space at the Universal Protein Resource (UniProt)
Rolf Apweiler et al.
NUCLEIC ACIDS RESEARCH (2012)
The many roles of IL-7 in B cell development; Mediator of survival, proliferation and differentiation
Steven A. Corfe et al.
SEMINARS IN IMMUNOLOGY (2012)
Bax: Addressed to kill
Thibaud T. Renault et al.
BIOCHIMIE (2011)
c-Abl regulates Mcl-1 gene expression in chronic lymphocytic leukemia cells
John C. Allen et al.
BLOOD (2011)
Bcl-2 family interaction with the mitochondrial morphogenesis machinery
M. M. Cleland et al.
CELL DEATH AND DIFFERENTIATION (2011)
Molecular analysis of neutrophil spontaneous apoptosis reveals a strong role for the pro-apoptotic BH3-only protein Noxa
S. Kirschnek et al.
CELL DEATH AND DIFFERENTIATION (2011)
Autophagy in tumorigenesis and energy metabolism: friend by day, foe by night
Robin Mathew et al.
CURRENT OPINION IN GENETICS & DEVELOPMENT (2011)
Mitochondria in Apoptosis: Bcl-2 Family Members and Mitochondrial Dynamics
Jean-Claude Martinou et al.
DEVELOPMENTAL CELL (2011)
The mitochondrial fission factor dynamin-related protein 1 modulates T-cell receptor signalling at the immune synapse
Francesc Baixauli et al.
EMBO JOURNAL (2011)
MicroRNA regulation of core apoptosis pathways in cancer
Raquel T. Lima et al.
EUROPEAN JOURNAL OF CANCER (2011)
Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis
Jessie Yanxiang Guo et al.
GENES & DEVELOPMENT (2011)
The Transcription Factor Myc Controls Metabolic Reprogramming upon T Lymphocyte Activation
Ruoning Wang et al.
IMMUNITY (2011)
Developmental Arrest of T Cells in Rpl22-Deficient Mice Is Dependent upon Multiple p53 Effectors
Jason E. Stadanlick et al.
JOURNAL OF IMMUNOLOGY (2011)
Defects in the Bcl-2-Regulated Apoptotic Pathway Lead to Preferential Increase of CD25lowFoxp3+ Anergic CD4+ T Cells
Yifan Zhan et al.
JOURNAL OF IMMUNOLOGY (2011)
Oncogenic Ras-Induced Expression of Noxa and Beclin-1 Promotes Autophagic Cell Death and Limits Clonogenic Survival
Mohamed Elgendy et al.
MOLECULAR CELL (2011)
The Soluble Form of Bax Regulates Mitochondrial Fusion via MFN2 Homotypic Complexes
Suzanne Hoppins et al.
MOLECULAR CELL (2011)
Non-apoptotic role of BID in inflammation and innate immunity
Garabet Yeretssian et al.
NATURE (2011)
Regulation of Neutrophil Survival/Apoptosis by Mcl-1
Eric Milot et al.
THESCIENTIFICWORLDJOURNAL (2011)
Elevated Mcl-1 perturbs lymphopoiesis, promotes transformation of hematopoietic stem/progenitor cells, and enhances drug resistance
Kirsteen J. Campbell et al.
BLOOD (2010)
Involvement of cytochrome c oxidase subunits Va and Vb in the regulation of cancer cell metabolism by Bcl-2
Z. X. Chen et al.
CELL DEATH AND DIFFERENTIATION (2010)
Life and death in the thymus-cell death signaling during T cell development
Jeniffer B. Hernandez et al.
CURRENT OPINION IN CELL BIOLOGY (2010)
Differential Dependence on Beclin 1 for the Regulation of Pro-Survival Autophagy by Bcl-2 and Bcl-xL in HCT116 Colorectal Cancer Cells
Muriel Priault et al.
PLOS ONE (2010)
Mcl-1 Is Essential for Germinal Center Formation and B Cell Memory
Ingela Vikstrom et al.
SCIENCE (2010)
The Bcl-2 family in autoimmune and degenerative disorders
Delphine Merino et al.
APOPTOSIS (2009)
Puma indirectly activates Bax to cause apoptosis in the absence of Bid or Bim
A. M. Jabbour et al.
CELL DEATH AND DIFFERENTIATION (2009)
Puma and to a lesser extent Noxa are suppressors of Myc-induced lymphomagenesis
E. M. Michalak et al.
CELL DEATH AND DIFFERENTIATION (2009)
Life and death by death receptors
Maria Eugenia Guicciardi et al.
FASEB JOURNAL (2009)
The role of BH3-only protein Bim extends beyond inhibiting Bcl-2-like prosurvival proteins
Delphine Merino et al.
JOURNAL OF CELL BIOLOGY (2009)
The T-cell-receptor signaling network
Morgan Huse
JOURNAL OF CELL SCIENCE (2009)
MEK/ERK-Mediated Phosphorylation of Bim Is Required to Ensure Survival of T and B Lymphocytes during Mitogenic Stimulation
Lorraine A. O'Reilly et al.
JOURNAL OF IMMUNOLOGY (2009)
Bak Activation for Apoptosis Involves Oligomerization of Dimers via Their α6 Helices
Grant Dewson et al.
MOLECULAR CELL (2009)
Stepwise Activation of BAX and BAK by tBID, BIM, and PUMA Initiates Mitochondrial Apoptosis
Hyungjin Kim et al.
MOLECULAR CELL (2009)
Mechanism of Bcl-2 and Bcl-XL inhibition of NLRP1 inflammasome: Loop domain-dependent suppression of ATP binding and oligomerization
Benjamin Faustin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Membrane Binding by tBid Initiates an Ordered Series of Events Culminating in Membrane Permeabilization by Bax
Jonathan F. Lovell et al.
CELL (2008)
Targeted deletion reveals essential and overlapping functions of the miR-17∼92 family of miRNA clusters
Andrea Ventura et al.
CELL (2008)
Bcl2 enhances induced hematopoietic differentiation of murine embryonic stem cells
Yan-Yi Wang et al.
EXPERIMENTAL HEMATOLOGY (2008)
Loss of the BH3-only protein Bmf impairs B cell homeostasis and accelerates γ irradiation-induced thymic lymphoma development
Verena Labi et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2008)
To trigger apoptosis, Bak exposes its BH3 domain and homodimerizes via BH3: Groove interactions
Grant Dewson et al.
MOLECULAR CELL (2008)
BAX activation is initiated at a novel interaction site
Evripidis Gavathiotis et al.
NATURE (2008)
Dual role of proapoptotic BAD in insulin secretion and beta cell survival
Nika N. Danial et al.
NATURE MEDICINE (2008)
Inhibition of the Bcl-xL Deamidation Pathway in Myeloproliferative Disorders
Rui Zhao et al.
NEW ENGLAND JOURNAL OF MEDICINE (2008)
Bid: a Bax-like BH3 protein
L. P. Billen et al.
ONCOGENE (2008)
MiR-15a and miR-16-1 cluster functions in human leukemia
George A. Calin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
How do BCL-2 proteins induce mitochondrial outer membrane permeabilization?
Jerry E. Chipuk et al.
TRENDS IN CELL BIOLOGY (2008)
The BCL2 rheostat in glucocorticoid-induced apoptosis of acute lymphoblastic leukemia
C. Ploner et al.
LEUKEMIA (2008)
Life and death during hematopoietic differentiation
Joseph T. Opferman
CURRENT OPINION IN IMMUNOLOGY (2007)
A three-helix homo-oligomerization domain containing BH3 and BH1 is responsible for the apoptotic activity of Bax
Nicholas M. George et al.
GENES & DEVELOPMENT (2007)
BH3-only proteins and BH3 mimetics induce autophagy by competitively disrupting the interaction between Beclin 1 and Bcl-2/Bcl-XL
Maria Chiara Maiuri et al.
AUTOPHAGY (2007)
Functional and physical interaction between Bcl-XL and a BH3-like domain in Beclin-1
M. Chiara Maiuri et al.
EMBO JOURNAL (2007)
The antiapoptotic protein Mcl-1 is essential for the survival of neutrophils but not macrophages
Ivan Dzhagalov et al.
BLOOD (2007)
DNA damage-induced Bcl-x(L) deamidation is mediated by NHE-1 antiport regulated intracellular pH
Rui Zhao et al.
PLOS BIOLOGY (2007)
Bim, Bad and Bmf: intrinsically unstructured BH3-only proteins that undergo a localized conformational change upon binding to prosurvival Bcl-2 targets
M. G. Hinds et al.
CELL DEATH AND DIFFERENTIATION (2007)
Orchestration of lymphocyte chemotaxis by mitochondrial dynamics
Silvia Campello et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2006)
Puma cooperates with Bim, the rate-limiting BH3-only protein in cell death during lymphocyte development, in apoptosis induction
Miriam Erlacher et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2006)
NF-κB and the immune response
M. S. Hayden et al.
ONCOGENE (2006)
Role of Bax and Bak in mitochondrial morphogenesis
Mariusz Karbowski et al.
NATURE (2006)
Mitochondria primed by death signals determine cellular addiction to antiapoptotic BCL-2 family members
Michael Certo et al.
CANCER CELL (2006)
Role for CED-9 and Egl-1 as regulators of mitochondrial fission and fusion dynamics
P Delivani et al.
MOLECULAR CELL (2006)
miR-15 and miR-16 induce apoptosis by targeting BCL2
A Cimmino et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy
S Pattingre et al.
CELL (2005)
Evasion of the p53 tumour surveillance network by tumour-derived MYC mutants
MT Hemann et al.
NATURE (2005)
Control of lymphocyte development by nuclear factor-κB
U Siebenlist et al.
NATURE REVIEWS IMMUNOLOGY (2005)
The BCL2A1 gene as a pre-T cell receptorinduced regulator of thymocyte survival
M Mandal et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
Obligate role of anti-apoptotic MCL-1 in the survival of hematopoietic stem cells
JT Opferman et al.
SCIENCE (2005)
Mechanisms of apoptosis through structural biology
N Yan et al.
ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY (2005)
Nomenclature of dynein light chain-linked BH3-only protein Bim isoforms
M Adachi et al.
CELL DEATH AND DIFFERENTIATION (2005)
Phagocytosis-induced apoptosis in macrophages is mediated by up-regulation and activation of the Bcl-2 homology domain 3-only protein Bim
S Kirschnek et al.
JOURNAL OF IMMUNOLOGY (2005)
Mitochondrial p53 activates Bak and causes disruption of a Bak-Mcl1 complex
JIJ Leu et al.
NATURE CELL BIOLOGY (2004)
Bim is a suppressor of Myc-induced mouse B cell leukemia
A Egle et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Extracellular signal-regulated kinases 1/2 are serum-stimulated BimEL kinases that bind to the BH3-only protein BimEL causing its phosphorylation and turnover
R Ley et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis
JE Chipuk et al.
SCIENCE (2004)
Selective disruption of lysosomes in HeLa cells triggers apoptosis mediated by cleavage of bid by multiple papain-like lysosomal cathepsins
T Cirman et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Mono- and multisite phosphorylation enhances Bcl2's antiapoptotic function and inhibition of cell cycle entry functions
XM Deng et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Transgenic expression of Bcl-2 modulates energy metabolism, prevents cytosolic acidification during ischemia, and reduces ischemia/reperfusion injury
K Imahashi et al.
CIRCULATION RESEARCH (2004)
Connecting proliferation and apoptosis in development and disease
DR Hipfner et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2004)
The first α helix of Bax plays a necessary role in its ligand-induced activation by the BH3-only proteins bid and PUMA
PF Cartron et al.
MOLECULAR CELL (2004)
Mcl-1 is required for Akata6 B-lymphoma cell survival and is converted to a cell death molecule by efficient caspase-mediated cleavage
J Michels et al.
ONCOGENE (2004)
An oncogenic tyrosine kinase inhibits DNA repair and DNAdamage-induced Bcl-X-L deamidation in T cell transformation
R Zhao et al.
CANCER CELL (2004)
Development and maintenance of B and T lymphocytes requires antiapoptotic MCL-1
JT Opferman et al.
NATURE (2003)
To be, or not to be:: NF-κB is the answer -: role of Rel/NF-κB in the regulation of apoptosis
J Kucharczak et al.
ONCOGENE (2003)
p53- and drug-induced apoptotic responses mediated by BH3-only proteins Puma and Noxa
A Villunger et al.
SCIENCE (2003)
Phosphorylation of Bim-EL by Erk1/2 on serine 69 promotes its degradation via the proteasome pathway and regulates its proapoptotic function
F Luciano et al.
ONCOGENE (2003)
Lysosomal membrane permeabilization induces cell death in a mitochondrion-dependent fashion
P Boya et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2003)
Combined deficiency of p50 and cRel in CD4+ T cells reveals an essential requirement for nuclear factor κB in regulating mature T cell survival and in vivo function
Y Zheng et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2003)
Essential role for the BH3-only protein Bim but redundant roles for Bax, Bcl-2, and Bcl-w in the control of granulocyte survival
A Villunger et al.
BLOOD (2003)
p53 has a direct apoptogenic role at the mitochondria
M Mihara et al.
MOLECULAR CELL (2003)
BID regulation by p53 contributes to chemosensitivity
JK Sax et al.
NATURE CELL BIOLOGY (2002)
Bid, Bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane
T Kuwana et al.
CELL (2002)
Bcl-XL deamidation is a critical switch in the regulation of the response to DNA damage
BE Deverman et al.
CELL (2002)
Deficiency in Bak and Bax perturbs thymic selection and lymphoid homeostasis
JC Rathmell et al.
NATURE IMMUNOLOGY (2002)
Induction and endoplasmic reticulum location of BIK/NBK in response to apoptotic signaling by E1A and p53
JP Mathai et al.
ONCOGENE (2002)
BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes
P Bouillet et al.
NATURE (2002)
Regulation and chance in the ontogeny of B and T cell antigen receptor repertoires
M Zemlin et al.
IMMUNOLOGIC RESEARCH (2002)
Degenerative disorders caused by Bcl-2 deficiency prevented by loss of its BH3-only antagonist bim
P Bouillet et al.
DEVELOPMENTAL CELL (2001)
BCL-2, BCL-XL sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis
EHYA Cheng et al.
MOLECULAR CELL (2001)
Pro-apoptotic cleavage products of Bcl-xL form cytochrome c-conducting pores in pure lipid membranes
G Basañez et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Bid is cleaved by calpain to an active fragment in vitro and during myocardial ischemia/reperfusion
M Chen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Apoptosis triggered by Myc-induced suppression of Bcl-XL or Bcl-2 is bypassed during lymphomagenesis
CM Eischen et al.
MOLECULAR AND CELLULAR BIOLOGY (2001)
PUMA, a novel proapoptotic gene, is induced by p53
K Nakano et al.
MOLECULAR CELL (2001)
Lysosomal protease pathways to apoptosis -: Cleavage of Bid, not pro-caspases, is the most likely route
V Stoka et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Molecular clocks
NE Robinson et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Posttranslational N-myristoylation of BID as a molecular switch for targeting mitochondria and apoptosis
JP Zha et al.
SCIENCE (2000)
Rationale for Bcl-xL/Bad peptide complex formation from structure, mutagenesis, and biophysical studies
AM Petros et al.
PROTEIN SCIENCE (2000)
The combined functions of proapoptotic Bcl-2 family members Bak and Bax are essential for normal development of multiple tissues
T Lindsten et al.
MOLECULAR CELL (2000)
Initiation of apoptosis by granzyme B requires direct cleavage of Bid, but not direct granzyme B-mediated caspase activation
VR Sutton et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2000)
NF-κB activation by the pre-T cell receptor serves as a selective survival signal in T lymphocyte development
RE Voll et al.
IMMUNITY (2000)
Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1
PF Dijkers et al.
CURRENT BIOLOGY (2000)
Phosphorylation of the pro-apoptotic protein BAD on serine 155, a novel site, contributes to cell survival
K Virdee et al.
CURRENT BIOLOGY (2000)
BAD Ser-155 phosphorylation regulates BAD/Bcl-XL interaction and cell survival
Y Tan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Regulation of BAD by cAMP-dependent protein kinase is mediated via phosphorylation of a novel site, Ser155
JM Lizcano et al.
BIOCHEMICAL JOURNAL (2000)
Nora, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis
E Oda et al.
SCIENCE (2000)
Posttranslational modification of Bcl-2 facilitates its proteasome-dependent degradation: Molecular characterization of the involved signaling pathway
K Breitschopf et al.
MOLECULAR AND CELLULAR BIOLOGY (2000)
Survival function of ERK1/2 as IL-3-activated, staurosporine-resistant Bcl2 kinases
XM Deng et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Bid induces the oligomerization and insertion of Bax into the outer mitochondrial membrane
R Eskes et al.
MOLECULAR AND CELLULAR BIOLOGY (2000)
分享论文
