期刊
NEUROIMAGE
卷 30, 期 1, 页码 285-298出版社
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.neuroimage.2005.09.025
关键词
remote memory; episodic memory; semantic memory; consolidation
资金
- NCRR NIH HHS [P41RR14075, P41 RR014075] Funding Source: Medline
- NINDS NIH HHS [R01 NS044623, NS44623, NS18741, R01 NS018741] Funding Source: Medline
Ecphory occurs when one recollects a past event cued by a trigger, such as a picture, odor, or name. It is a central component of autobiographical memory, which allows us to travel mentally back in time and reexperience specific events from our personal past. Using fMRI and focusing on the role of medial temporal lobe (MTL) structures, we investigated the brain bases of autobiographical memory and whether they change with the age of memories. Importantly, we used an ecphory task in which the remote character of the memories was ensured. The results showed that a large bilateral network supports autobiographical memory: temporal lobe, temporo-parieto-occipital junction, dorsal prefrontal cortex, medial frontal cortex, retrosplenial cortex and surrounding areas, and MTL structures. This network, including MTL structures, changed little with the age of the memories. (c) 2005 Elsevier Inc. All rights reserved.
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