期刊
ANIMAL MODELS: THEIR VALUE IN PREDICTING DRUG EFFICACY AND TOXICITY
卷 1245, 期 -, 页码 E1-E5出版社
BLACKWELL SCIENCE PUBL
DOI: 10.1111/j.1749-6632.2011.06382.x
关键词
systems pharmacology; network biology; personalized medicine
资金
- NIH [GM-54508, 071558]
- NIGMS [T32-GM062754]
Systems pharmacology approaches can be used to identify and predict drug-induced adverse events. Disease-centered networks within the human interactome allow us to predict which drugs may produce a similar pathophysiology. Such predictions can be tested in animal models.
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