期刊
AMERICAN JOURNAL OF OPHTHALMOLOGY
卷 141, 期 3, 页码 446-455出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.ajo.2005.08.063
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资金
- Intramural NIH HHS [ZIA EY000403-10, Z99 EY999999, ZIA EY000403-13, ZIA EY000403-14, ZIA EY000403-11, Z01 EY000403-07, Z01 EY000403-06, ZIA EY000403-15, ZIA EY000403-09, ZIA EY000403-08, ZIA EY000403-12] Funding Source: Medline
- NHLBI NIH HHS [N01HC95165, N01 HC095162, N01 HC095169, N01 HC095163, R01 HL069979, N01 HC095165, N01HC95169, N01 HC095159, N01HC95159, N01 HC095161, N01 HC095160, N01 HC095164, HL 69979-03, R01 HL069979-03] Funding Source: Medline
PURPOSE: To describe the prevalence and risk factors of diabetic retinopathy in a multi,ethnic US population of whites, blacks, hispanics, and chinese. DESIGN: Cross-sectional study of 778 individuals from ages 45 to 85 years with diabetes, participating in the Multi-Ethnic Study of Atherosclerosis (MESA). METHODS: Retinal photographs were obtained with a 45 degrees nonmydriatic digital fundus camera. Presence and severity of diabetic retinopathy were graded at a central reading center on the basis of a modification of the Airlie House classification system. All participants underwent a standardized interview, examination, and laboratory investigations. RESULTS: In this population with diabetes, the prevalence of any retinopathy was 33.2% and macular edema 9.0%. The prevalence of any diabetic retinopathy and macular edema was significantly higher in blacks (36.7% and 11.1%) and hispanics (37.4% and 10.7%) than in whites (24.8% and 2.7%) and chinese (25.7% and 8.9%) (P =.01 and P =.007, comparing racial/ethnic differences for retinopathy and macular edema, respectively). Significant independent predictors of any retinopathy were longer duration of diabetes, higher fasting serum glucose, use of diabetic oral medication or insulin, and greater waist-hip ratio. Race was not an independent predictor of any retinopathy. CONCLUSIONs: This study provides contemporary data on the prevalence of and risk factors for diabetic retinopathy among whites, blacks, hispanics, and chinese participating in the MESA.
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