期刊
LONGEVITY, REGENERATION, AND OPTIMAL HEALTH: INTEGRATING EASTERN AND WESTEN PERSPECTIVES
卷 1172, 期 -, 页码 110-114出版社
BLACKWELL PUBLISHING
DOI: 10.1111/j.1749-6632.2009.04499.x
关键词
basement membrane; blastema; inflammation; MRL mouse; matrix metalloproteinases; neutrophils; regeneration; cognitive-behavioral; meditation
资金
- NCI NIH HHS [P30 CA010815] Funding Source: Medline
- NATIONAL CANCER INSTITUTE [P30CA010815] Funding Source: NIH RePORTER
The matrix metalloproteinases (MMPs) have been implicated in the regenerative response in amphibians and various mammalian models of regeneration. The neutrophil response is known to bring MMPs and other proteases to the wound to promote bacterial elimination and tissue remodeling. These issues in relation to what is occurring in the MRL mouse model of regeneration/wound healing are discussed, followed. by speculation as to their possible relevance for examples of the putative scarless wound healing described by some medical anthropologists and clinicians.
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