Efficient synthesis of 1,4-disubstituted 1,2,3-triazoles in ionic liquid/water system

A copper(I) catalyst in a mixture of the ionic liquid [bmim][BF4] and water, can effect three-component reaction of halides, sodium azide and alkynes to form 1,4-disubstituted 1,2,3-triazoles in good to high yields. The method is efficient and environmentally friendly. (c) 2006 Elsevier Ltd. All rights reserved.