期刊
TROPICAL MEDICINE & INTERNATIONAL HEALTH
卷 11, 期 4, 页码 490-503出版社
WILEY
DOI: 10.1111/j.1365-3156.2006.01594.x
关键词
spatial distribution; maps; Bayesian analysis; Schistosoma haematobium; Schistosoma mansoni; schistosomiasis; communicable disease control; Tanzania
资金
- Wellcome Trust [073656] Funding Source: Medline
OBJECTIVE To predict the spatial distributions of Schistosoma haematobium and S. mansoni infections to assist planning the implementation of mass distribution of praziquantel as part of an on-going national control programme in Tanzania. METHODS Bayesian geostatistical models were developed using parasitological data from 143 schools. RESULTS In the S. haematobium models, although land surface temperature and rainfall were significant predictors of prevalence, they became non-significant when spatial correlation was taken into account. In the S. mansoni models, distance to water bodies and annual minimum temperature were significant predictors, even when adjusting for spatial correlation. Spatial correlation occurred over greater distances for S. haematobium than for S. mansoni. Uncertainties in predictions were examined to identify areas requiring further data collection before programme implementation. CONCLUSION Bayesian geostatistical analysis is a powerful and statistically robust tool for identifying high prevalence areas in a heterogeneous and imperfectly known environment.
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