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Sources of cardiomyocytes for stem cell therapy: An update

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PEDIATRIC RESEARCH
卷 59, 期 4, 页码 79R-83R

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NATURE PUBLISHING GROUP
DOI: 10.1203/01.pdr.0000203551.63437.9b

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  1. NHLBI NIH HHS [HL078797-01A1] Funding Source: Medline

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The therapeutic use of stern cells for cardiac repair following myocardial infarction (MI) has generated a great deal of interest. Many types of stem/progenitor cells have been used in in attempt to regenerate the infarcted heart. We have reviewed the Current state of progress using embryonic stern (ES) cells, hemato-poietic stem and progenitor cells (HSCs/HPCs), mesenchymal stern and progenitor cells, resident and cardiac '' stem '' cells from other Sources. Our view is that, even though the road ahead is long and tortuous, embryonic stem cells represent the most reliable font of CMC and the most promising type of cell to rely on for a future tool in heart failure treatment.

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