期刊
SEMINARS IN FETAL & NEONATAL MEDICINE
卷 11, 期 2, 页码 127-137出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.siny.2005.11.007
关键词
prematurity; very-low-birth-weight; extremely low birth weight; adult outcomes
类别
资金
- NCRR NIH HHS [M01 RR00080] Funding Source: Medline
- NICHD NIH HHS [R01 HD34177] Funding Source: Medline
Information on the young adult outcomes of the initial survivors of neonatal intensive care has been reported from the United States, Canada, Australia, Great Britain and other European countries. The studies have varied with regard to whether they were regional or hospital-based, their birth-weight group and gestational age, rates of survival, socio-demographic background, and measures of assessment and types of outcome studied. Despite these differences the overall results reveal that neurodevelopment and growth sequelae persist to young adulthood. Very-low-birth-weight young adults have, with few exceptions, poorer educational achievement than normal-birth-weight controls, and fewer continue with post-high-schoot study. Rates of employment are, however, similar. There are no major differences in general health status, but the young adults demonstrate poorer physical abilities, higher mean blood pressure and poorer respiratory function. There is no evidence of major psychiatric disorder, although anxiety and depression are reported more often. The young adults report less risk-taking than control populations. They report fairly normal social lives and quality of life. When differences are noted they are usually due to neurosensory disabilities. Longer-term studies are needed to evaluate ultimate educational and occupational achievement. It will also be important to assess the effects of preterm birth, early growth failure and catch-up growth on later metabolic and cardiovascular health. (c) 2005 Elsevier Ltd. ALL rights reserved.
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