期刊
AMERICAN JOURNAL OF CLINICAL PATHOLOGY
卷 125, 期 4, 页码 555-581出版社
OXFORD UNIV PRESS INC
DOI: 10.1309/UC6KQHLD9LV2KENN
关键词
osteosarcoma; malignant bone tumors; bones; imaging
类别
资金
- NCI NIH HHS [CA93796, CA98543] Funding Source: Medline
- NIAMS NIH HHS [AR46031] Funding Source: Medline
Osteosarcoma is the most common primary tumor of bone, yet its absolute incidence among malignant tumors is low. Within its strict histologic, definition, osteosarcoma comprises a family of lesions with considerable diversity in histologic features and grade. Its prognosis is dependent not only on these parameters but also on its anatomic site. It may occur inside the bones (in the intramedullary or intracortical compartment), on the surfaces of bones, and in extraosseous sites. Information of diagnostic or prognostic significance has not been elucidated from studies of its cytogenetics. This review summarizes the anatomic and histologic variations of osteosarcoma and offers a schema for its subclassification.
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