期刊
PSYCHOLOGICAL MEDICINE
卷 36, 期 4, 页码 475-484出版社
CAMBRIDGE UNIV PRESS
DOI: 10.1017/S0033291705006884
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Background. Formal thought disorder (FTD) has long been regarded as a key sign of schizophrenia but little is known about its origins or aetiology. One Suggestion is that it is directly related to disordered lauguage functioning; a second is that it is a reflection of poor neurocognitive functioning. A current model posits that it is related to a combination of executive dysfunction and impaired semantic processing. Method. To examine these alternative ideas, a heterogeneous group of 30 patients, all carrying a diagnosis of schizophrenia, and 18 non-patient controls completed a series of neurocognitive and pyscholinguistic tests, and a clinical review that, inter cilia, permitted assessment of thought disorder (TD) using the Thought, Language and Communication Scale (TLC). Results. Patients generally performed at a lower level on most components of the test battery, but there was little evidence of a relationship between TD and syntactic pyscholinguistic function. However, schizophrenic patients manifesting higher levels of TD performed at a lower level on tests sensitive to executive dysfunction and semantic impairments. Conclusions. The origins of TD seem more closely linked to deficits in executive functioning and semantic processing than to impairments in Other language functions or general cognition.
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