Abietane diterpenoid dimers from the roots of Salvia prionitis

Three abietane diterpenoid dithers, bisprioterones A-C (1-3), were isolated from roots of the Chinese folk medicinal plant Salvia prionitis Hance (Labiatae). Compounds 1-3 possessed two different abietane diterpenoid skeleta, which were linked via either a C-C single bond (1 and 2) or an ether bridge (3). Their structures were elucidated by analysis of 1 D and 2D NMR spectroscopic data. The structure of 1 was further confirmed by a single-crystal X-ray diffraction determination. (c) 2005 Elsevier Ltd. All rights reserved.