期刊
ORGANIC LETTERS
卷 8, 期 8, 页码 1553-1556出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol060002+
关键词
-
资金
- NCRR NIH HHS [G12 RR003060, 5G12 RR03060-20] Funding Source: Medline
General, high-yield tandem electrophilic fluorination and modified Julia olefination for the synthesis of fluoro olefins is reported. A series of alpha-fluoro 1,3-benzothiazol-2-yl sulfone-based synthons were synthesized via deprotonation-fluorination. Of critical importance for high-yield fluorinations were heterogeneous reaction conditions, as under homogeneous conditions only starting sulfones were recovered. The alpha-fluoro 1,3-benzothiazol-2-yl sulfones so obtained were subjected to condensations with a variety of aldehydes and ketones to afford high yields of regiospecifically fluorinated olefins.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据