期刊
CHEMISTRY-A EUROPEAN JOURNAL
卷 12, 期 13, 页码 3596-3609出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/chem.200501180
关键词
allylic substitution; asymmetric catalysis; chiral ligands; iridium; phosphoramidite
A new phosphoramidite ligand was used in the iridium-catalyzed allylic substitution reaction. This permitted high regio- and enantioselectivities on a wide variety of substrates and nucleophiles. Because of the stereospecificity of the reaction obtained by using branched substrates, a kinetic resolution reaction was attempted. The origin of the impressive efficiency of this ligand in terms of kinetics was explored in detail, as was the role of the substituent in the ortho-position of the amine moiety.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据