We present a three-dimensional (3D) endoscopic optical coherence tomography (OCT) system based on a dual-axis scanning microelectromechanical system (MEMS) mirror. The diameter of the MEMS mirror was 1.2 mm and both axes were capable of scanning greater than 20 degrees with linearity. The endoscopic MEMS probe was integrated with an OCT system and volume images were obtained at a rate of 3 frames/s by means of two-axis lateral scanning combined with an axial scan. In the initial investigations, 3D OCT images of healthy rabbit trachea as well as images of normal and cancerous regions of hamster cheek pouch tissue were obtained. (c) 2006 American Institute of Physics.
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